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Basic

Elucidating the role of Hedgehog signaling during hereditary multiple exostoses pathogenesis

9 December 202525 November 2021 by Sarah Catheline
Categories HubLE Archive Tags ASBMR, ASBMR 2021, Basic, cartilage, chondrocyte, hereditary multiple exostoses, orthopaedics, rare diseases Leave a comment

The contribution of NADPH oxidase 2-dependent reactive oxygen species to bone mass maintenance and formation

9 December 202511 November 2021 by Nicole Gould
Categories HubLE Archive Tags ASBMR, ASBMR 2021, Basic, Bone mass, NADPH oxidase 2, osteocyte, Reactive oxygen species Leave a comment

Effect of FNDC5/ Irisin on osteocytes

9 December 202511 November 2021 by Anika Shimonty
Categories HubLE Archive Tags ASBMR, ASBMR 2021, Basic, bone, FNDC5, irisin, mouse model, muscle, myokine, osteocytes

Deciphering the role of aging microtubules on osteocyte mechanotransduction

9 December 20257 November 2021 by Jenna Leser
Categories HubLE Archive Tags aging, ASBMR, ASBMR 2021, Basic, mechanotransduction, microtubules, osteocyte, osteopenia, Translational Leave a comment

Association between hydroxyproline bound water and bone mechanics

9 December 20251 July 2021 by Mustafa Unal
Categories HubLE Archive Tags Basic, biomechanics, Bone Matrix, Bone Mechanics, Bone Quality, ECTS, ECTS 2021, Hydroxyproline, Raman Spectroscopy, Water Leave a comment

Characterization of osteoclast diversity to unravel functional differences and to identify selective targeting options

9 December 20259 June 2021 by Julia Halper
Categories HubLE Archive Tags Basic, ECTS, ECTS 2021, osteoclast, Osteoclastogenesis, osteoprogenitors

Generating Craniosynostosis disease models with Prime-editing

9 December 20258 June 2021 by Max Gijsbertsen
Categories HubLE Archive Tags Basic, Craniosynostosis, DNA, ECTS, ECTS 2021, genome, mutation, Prime-editing Leave a comment

Metabolic regulation of chondrocyte function during bone development

9 December 20257 June 2021 by Steve Stegen
Categories HubLE Archive Tags amino acid, Basic, cartilage, chondrocyte, chondrocyte proliferation, ECTS, ECTS 2021, glutamine, Metabolic regulation, serine Leave a comment

Tissue-level mechanical stimuli drive bone formation and resorption in humans and mice

9 December 20254 June 2021 by Matthias Walle
Categories HubLE Archive Tags Basic, bone formation, Bone mechanoregulation, bone remodeling, bone resorption, diabetes, ECTS, ECTS 2021, loading, Longitudinal high-resolution computed tomography, mechanical signal, Translational Leave a comment

CRISPR/Cas9 mediated fluorescent reporter mice for osteoblasts and osteoclasts to study bone mechanomics

9 December 20253 June 2021 by Dilara Yilmaz
Categories HubLE Archive Tags Age-related osteoporosis, Basic, bone adaptation, CRISPR/Cas9, ECTS, ECTS 2021, fluorescent, osteoblast, osteoclast, Reporter mice model
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